This course is a 1 unit optional laboratory counterpart to “Genomics” (HMGP 7620) offered in the School of Medicine at UC Denver for Spring 2010.  The objective of this unit will be to give students with little programming or Linux/UNIX proficiency enough background and hands-on experience to be able to: write simple scripts to obtain, reformat, and process large genomic data sets, perform basic data manipulation including sequence alignment, mapping, assembly, and homology-based search, and to extract meaningful information from pattens of intra- and inter-specific genomic variation using phylogenetic methods, simulation, and advanced statistical techniques.